Recombinant Human Cadherin-11/OB-Cadherin/CDH11 (C-Fc-6His)

Recombinant Human Cadherin-11/OB-Cadherin/CDH11 (C-Fc-6His)

SKU: CB83-10ug
Recombinant Human Cadherin-11 is produced by our Mammalian expression system and the target gene encoding Phe23-Thr617 is expressed with a Fc, 6His tag at the C-terminus. Bon Opus Cat. #CB83
  • Accession Number

  • Background

    Cadherin-11, also known as OSF-4, Osteoblast cadherin and CDH11, is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
  • Expression

    Human Cells
  • Packaging

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
  • ALTnames

    Cadherin-11, OSF-4, Osteoblast cadherin, CDH11,
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