Recombinant Human Brain-Derived Neurotrophic Factor/BDNF
Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed. Bon Opus Cat. #C076
BackgroundBrain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
ALTnamesBrain-Derived Neurotrophic Factor, BDNF, Abrineurin