LinkLight™ U2-OS S1PR4 / β-arrestin Cell Line

LinkLight™ U2-OS S1PR4 / β-arrestin Cell Line

SKU: BC050018
$17,000.00Price
LinkLight™ U2-OS S1PR4 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human S1PR4 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method. Bon Opus Cat. #BC050018
Size
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Asn331-Val524
C-mFc
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
S protein RBD; 2019-nCoV S protein RBD
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Asn331-Val524
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Pro589
C-mFc
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Ser591(Val367Phe)
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Phe541(F342L)
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.Some findings indicated that the mutated viruses may be evolved to acquire remarkably increased infectivity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Phe541(N354D)
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.Some findings indicated that the mutated viruses may be evolved to acquire remarkably increased infectivity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Phe541(V367F)
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.Some findings indicated that the mutated viruses may be evolved to acquire remarkably increased infectivity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Phe541(R408I)
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.Some findings indicated that the mutated viruses may be evolved to acquire remarkably increased infectivity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Phe541(A435S)
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.Some findings indicated that the mutated viruses may be evolved to acquire remarkably increased infectivity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Phe541(K458R)
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.Some findings indicated that the mutated viruses may be evolved to acquire remarkably increased infectivity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Phe541(G476S)
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.Some findings indicated that the mutated viruses may be evolved to acquire remarkably increased infectivity.
Accession Number
QHD43416.1
Endotoxin
Species
Expression System
NA
SARS-CoV-2
Human Cells
Target Sequence
Tag
Arg319-Phe541(V483A)
C-6His
Formulation
Packaging
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Dry ice/ice packs
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Background
Alternative Names
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.Some findings indicated that the mutated viruses may be evolved to acquire remarkably increased infectivity.