LinkLight™ HEK293 PTH1R GPCR/14-3-3 Cell Line
LinkLight™ HEK293 PTH1R GPCR/14-3-3 Cell Line is a stable monoclonal cell line in HEK293 cells, targeting Human PTH1R pathway via 14-3-3. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method. Bon Opus Cat. #BC050069
BackgroundPTH1R acts as a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). It is a member of the G-protein coupled receptor family 2. Activity is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis.
PackagingShip on Dry Ice
ALTnamesPTH1R, Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor, PTHR, PTHR1