Biotinylated Recombinant Human Transforming Growth Factor Beta-2 Proprotein is produced by our Mammalian expression system and the target gene encoding Leu30- Ser390 (Cys33Ser) is expressed with a 8His, Avi tag at the N-terminus.

Biotinylated Human Latent TGF-beta 2 (N-8His-Avi)

Name: Biotinylated Human Latent TGF-beta 2 (N-8His-Avi)
SKU: CY99-20ug
Price: 799 USD
Availability: InStock

SKU: CY99-20ug

$799.00

Size

Quantity

[{"key":"CY99-100ug","value":"Backorder"},{"key":"CY99-20ug","value":"Backorder"}]

FAQ

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Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

Less than 0.1 EU/ug

Accession Number

P61812

Species

Human

Expression System

Human cells

Target Sequence

Leu21-Ser414 (Cys24Ser)

N-8His-Avi

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Packaging

Ambient

Background

Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGFB2 could be a potential biomarker for screening, surveillance and prognosis in GC, and that TGFB2 might drive EMT in GC through the NGF/TrKs pathway. Overexpression of TGFB2 may drive EMT through the neuriterelated signaling and affect TMB levels by regulating the DNA damage repair pathways and immune infiltrates.TGF-β2 is an immune suppressor involvedin the development of immune tolerance, and recombinant TGF-β2 incubation is more potent than TGF-β1 or TGF-β3 incubation in suppressing macrophage inflammatory responses.