WDR5 Recombinant Rabbit monoclonal Antibody IgG
Fig1: Western blot analysis of WDR5 on different cell lysates using anti-WDR5 antibody at 1/1,000 dilution.
Lane 1: Hela Lane 2: A549 Lane 3: NIH-3T3 Lane 4: PC-12
Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-WDR5 antibody. Counter stained with hematoxylin.
Fig3: Flow cytometric analysis of Hela cells with WDR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, IHC, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesWD repeat-containing protein 5, BMP2-induced 3-kb gene protein
BackgroundContributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.(ET1705-60)