VDAC1 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on different cell lysates using anti-VDAC1 rabbit polyclonal antibodies.
Fig2: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-VDAC1 rabbit polyclonal antibody.
Fig3: ICC staining VDAC1 in Hela cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).
Host Species; Species ReactivityRabbit; Human, Zebrafish
Application SummaryWB, ICC, IHC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesVoltage-dependent anion-selective channel protein 1，Outer mitochondrial membrane protein porin 1，Plasmalemmal porin，Porin 31HL，Porin 31HM
BackgroundVoltage-dependent anion-selective channel (VDAC1) (also referred to as porin, isoform 1) is a small protein, originally discovered in the outer membrane of mitochondria where it constitutes the major pore-forming protein. The porin protein VDAC1 allows to the outer-most membrane of the mitochondrion free permeability to low molecular-weight solutes. VDAC1 has been shown to co-immunoprecipitate with the anti-apoptotic protein Bcl-2 and suggested to be involved in forming the mitochondrial pore which releases cytochrome c during apoptosis.(R1307-1)