UTF1 Rabbit polyclonal Antibody IgG

SKU: BA110696-100µl

Fig1: Western blot analysis on D3 cell lysates (1) and human brain tissue (2) using anti-UTF1 rabbit polyclonal antibodies.

Fig2: Immunohistochemical analysis of paraffin-embedded human testis tissue using anti- UTF1 rabbit polyclonal antibodies.


Bon Opus Cat. #BA110696
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

  • Application Summary

    WB, IHC
  • Purification; Formulation

    Immunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Undifferentiated embryonic cell transcription factor 1
  • Background

    Undifferentiated embryonic cell transcription factor 1 (UTF1) is expressed in cells of the inner cell mass and the epiblast. Upon activation by Oct-3/4, UTF1 may be responsible for the rapid proliferation and tumorigenic properties of embryonic stem cells. Sox2 is also part of the Oct-3/4-containing complex able to bind the regulatory region of UTF1. UTF1 acts as a transcriptional coactivator of ATF2 and it binds to the N-terminal region of ATF2. Reduced expression in embryonic stem cells (ESCs) is associated with failure to differentiate properly, although self-renewal is unaffected.(R1305-4)

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