TTR Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112185-100µl
$279.00Price

Fig1: Western blot analysis of TTR on different cells lysates using anti-TTR antibody at 1/500 dilution.

Positive control: 

  Line 1: Human brain 

  Line 2;Human lung

Fig2: ICC staining TTR in A549 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: ICC staining TTR in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Bon Opus Cat. #BA112185
Size
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IP, ICC/IF, IHC, FC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Transthyretin, ATTR, Prealbumin, TBPA
  • Background

    Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein). The gene encoding Prealbumin maps to human chromosome 18q12.1.(ET1703-83)

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