TMEM39a Rabbit polyclonal Antibody IgG
Fig1: Immunocytochemical staining of Hela cells using anti-TMEM39a rabbit polyclonal antibody.
Fig2: Immunocytochemical staining of PANC-1 cells using anti-TMEM39a rabbit polyclonal antibody.
Fig3: Immunohistochemical analysis of paraffin- embedded human pancreas tissue using anti-TMEM39a rabbit polyclonal antibody.
Host Species; Species ReactivityRabbit; Human, Mouse
Application SummaryICC, IHC, FC
Purification; FormulationPeptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesTransmembrane protein 39A
BackgroundTMEM39A is a 146 amino acid protein encoded by a gene mapping to human chromosome 3. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.(R1510-16)