TLR7 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis of TLR7 on different cell lysates using anti-TLR7 antibody at 1/1000 dilution.
Lane 1: Raji
Lane 2: Daudi
Lane 3: Jurkat
Lane 4: THP-1
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-TLR7 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-TLR7 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, IHC
Purification; FormulationPeptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesToll-like receptor 7
BackgroundMembers of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. TLR7, 8 and 9 form a group of structurally related TLR family members that are localized to intracellular endosomes . TLR7 shows highest expression in lung, placenta, and spleen. TLR7 mediates responses to a class of synthetic compounds, including imidazoquinolines, guanosine-based drugs that induce anti-viral responses.(ER30606)