Synaptophysin Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis of Synaptophysin on mouse brain tissue lysate using anti-Synaptophysin antibody at 1/2,000 dilution.
Fig2: ICC staining Synaptophysin (red) in PANC-1 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: Immunohistochemical analysis of paraffin-embedded rat pancreas cancer tissue using anti-Synaptophysin antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityMouse; Mouse, Rat
ImmunogenSynthetic Peptide (KLH-coupled) within human Synaptophysin 220-280 aa.
Application SummaryWB, ICC, IHC, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesSynaptophysin,BM89 antigen,Major synaptic vesicle protein p38
BackgroundSynaptophysin is a 38 kDa glycoprotein present in the membrane of neuronal presynaptic vesicles in brain, spinal cord, retina, vesicles of adrenal medulla, neuromuscular junctions, and endocrine cells. It is also expressed by neuroendocrine cells throughout the body, both normal and neoplastic. Synaptophysin is a useful marker for the identification of normal neuroendocrine cells and neuroendocrine neoplasms.(M0407-30)