(800) 943-6396

150 Essex St, Millburn, NJ 07041, USA

©2019 by Bon Opus Biosciences, LLC.

STIP1 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112535-100µl
$279.00Price

Fig1: Western blot analysis of STIP1 on Mouse testis and Rat testis lysates using anti-STIP1 antibody at 1/500 dilution.

Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-STIP1 antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-STIP1 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA112535
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB,IHC,FC,IP,ICC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Stress-induced-phosphoprotein 1, Hsc70/Hsp90-organizing protein, Renal carcinoma antigen NY-REN-11, Transformation-sensitive protein IEF SSP 3521
  • Background

    Stress-induced-phosphoprotein 1 (STI1) functions as a co-chaperone for HSP70 and HSP90 during heat shock response. STI1 exists as either a monomer or a dimer, and this conformational flexibility facilitates its function in organizing HSP70/HSP90. HSP90 acts as an ATPase, and requires the recruitment of client proteins and proper conformation to function. STI1 acts as a "scaffold" for client protein recruitment to the relaxed, ADP-bound conformation of HSP90, thus suppressing ATP turnover during the loading phase and allowing proper function.(ET7107-63)