Stella Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on cell lysates using anti-Stella rabbit polyclonal antibodies.
Fig2: Immunohistochemical analysis of paraffin-embedded mouse teratoma tissue using anti-Stella rabbit polyclonal antibody.
Host Species; Species ReactivityRabbit; Human, Mouse, Zebrafish
Application SummaryWB, IHC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesDevelopmental pluripotency-associated protein 3,Stella-related protein
BackgroundStella is a primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. It participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. It is important for the totipotent/pluripotent states continuing through preimplantation development.(R1306-1)