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STAT6 Rabbit polyclonal Antibody IgG

SKU: BA110630-100µl

Fig1: Western blot analysis of STAT6 on different cell lysates using anti-STAT6 antibody at 1/1000 dilution.

Positive control: 

  Lane 1: Raji 

  Lane 2: Daudi 

  Lane 3: Hela 

  Lane 4: Ags 

  Lane 5: Jurkat

Fig2: ICC staining STAT6 in Hela cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-STAT6 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA110630
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

  • Application Summary

    WB, ICC, IHC, FC
  • Purification; Formulation

    Peptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Signal transducer and activator of transcription 6,IL-4 Stat
  • Background

    In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein STAT6 plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.(ER40121)