SSTR3 Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis of SSTR3 on human SSTR3 recombinant protein using anti-SSTR3 antibody at 1/1,000 dilution.
Fig2: Western blot analysis of SSTR3 on HEK293 (1) and SSTR3-hIgGFc transfected HEK293 (2) cell lysate using anti-SSTR3 antibody at 1/1,000
Fig3: Western blot analysis of SSTR3 on different cell lysate using anti-SSTR3 antibody at 1/1,000 dilution.
Positive control: Line1: Hela Line2: PANC-1 Line3: PC-12 Line4: SK-N-SH Line5: U937 Line6: HepG2
Host Species; Species ReactivityMouse; Human
Application SummaryWB, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnames3-phosphoinositide-dependent protein kinase 1
BackgroundThere are five somatostatin receptor subtypes termed SSTR 1 to 5. They are G protein coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary. Somatostatin receptor type 3 (SSTR3) is a Somatostatin Receptor. Unlike SSTR1 and SSTR2, SSTR3 is functionally coupled to adenylyl cyclase. Expression of SSTR3 has been reported in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid.(EM1706-39)