SOX2 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on F9 (A) and MCF-7(B) cell lysates using anti-SOX2 rabbit polyclonal antibody.
Fig2: ICC image of SOX2 antibody stained human F9 cells (A) and NCCIT cells (B). The secondary antibody (green) was goat anti-rabbit IgG (H+L) FITC conjugated.
Host Species; Species ReactivityRabbit; Human, Mouse
Application SummaryWB, IHC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesTranscription factor SOX-2
BackgroundSRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. Sox2, Oct-4 and Nanog co-operate in this network, and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency. POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells(R1106-1)