SOX10 Mouse monoclonal Antibody IgG1
Fig1: 1: Western blot analysis on F9 (1) and mouse fetal brain (2) cell lysates using anti-SOX10 Mouse mAb.
Fig2: Immunohistochemical analysis of paraffin-embedded mouse fetal brain (13.5 days) tissue using anti- SOX10 Mouse mAb.
Host Species; Species ReactivityMouse; Mouse
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesTranscription factor SOX-10,Protein SOX-21,Transcription factor SOX-M
BackgroundTranscription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease(M1311-1)