SOCS2 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112601-100µl
$279.00Price

Fig1: Western blot analysis of SOCS2 on different lysates using anti-SOCS2 antibody at 1/1,000 dilution.

 Positive control:

 Lane 1: Human placenta 

  Lane 2: SH-SY-5Y

 

Fig2: ICC staining SOCS2 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: ICC staining SOCS2 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Bon Opus Cat. #BA112601
Size
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

    Recombinant protein within human SOCS2 1-150aa.
  • Application Summary

    WB,ICC,IF,IP
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Suppressor of cytokine signaling 2, Cytokine-inducible SH2 protein 2, STAT-induced STAT inhibitor 2
  • Background

    SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.(ET7108-40)

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