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smooth muscle Myosin heavy chain 11 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112260-100µl
$279.00Price

Fig1: ICC staining smooth muscle Myosin heavy chain 11 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig2: ICC staining smooth muscle Myosin heavy chain 11 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: Immunohistochemical analysis of paraffin-embedded human jejunum tissue using anti-smooth muscle Myosin heavy chain 11 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA112260
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC, ICC/IF
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Myosin-11, Myosin heavy chain 11, Myosin heavy chain, smooth muscle isoform, SMMHC
  • Background

    Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits, which is expressed by my calcium and calmodulin-dependent phosphorylation of Myosin light chain (MLC) Myosin heavy chains, encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the Speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on th E functional activity of the muscle.(ET1704-61)