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Smad2 Rabbit polyclonal Antibody IgG

SKU: BA110740-100µl
$279.00Price

Fig1: Immunocytochemical staining of SW480 cells using anti-Smad2 rabbit polyclonal antibody.

Fig2:  Immunocytochemical staining of SK-BR-3 cells using anti-Smad2 rabbit polyclonal antibody.

Fig3:  Immunocytochemical staining of HepG2 cells using anti-Smad2 rabbit polyclonal antibody.

Bon Opus Cat. #BA110740
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Peptide
  • Application Summary

    ICC, IHC
  • Purification; Formulation

    Peptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Mothers against decapentaplegic homolog 2, JV18-1, Mad-related protein 2, SMAD family member 2
  • Background

    Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGF∫/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF∫ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGF∫ signaling by interfering with TGF∫-mediated phosphorylation of other Smad proteins.(R1511-29)