SFRP4 Recombinant Rabbit monoclonal Antibody IgG
Fig1: Western blot analysis of SFRP4 on different lysates using anti-SFRP4 antibody at 1/1,000 dilution.
Lane 1: Mouse testis
Lane 2: A549
Lane 3: HepG2
Lane 4: SH-SY-5Y
Fig2: Flow cytometric analysis of A549 cells with SFRP4 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
ImmunogenFull length Recombinant protein of human SFRP4.
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesSecreted frizzled-related protein 4, Frizzled protein, human endometrium
BackgroundSoluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.(ET7109-27)