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SFRP1 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112230-100µl
$279.00Price

Fig1: Western blot analysis of SFRP1 on human kidney cells lysates using anti-SFRP1 antibody at 1/500 dilution.

 

 

Bon Opus Cat. #BA112230
Size
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

    Recombinant protein
  • Application Summary

    WB
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Secreted frizzled-related protein 1, Secreted apoptosis-related protein 2
  • Background

    Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.(ET1704-29)