SCNN1G Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis of SCNN1G on A431 cell lysate using anti-SCNN1G antibody at 1/1,000 dilution.
Fig2: ICC staining SCNN1G in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining SCNN1G in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
ImmunogenRecombinant protein within human SCNN1G aa 250-350.
Purification; FormulationProtein affinity purified.; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesAmiloride-sensitive sodium channel subunit gamma, Epithelial Na(+) channel subunit gamma, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG
BackgroundSodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.(ER1803-61)