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SCAI Mouse monoclonal Antibody IgM

SKU: BA110795-100µl
$279.00Price

Fig1: Western blot analysis of SCAI on Recombinant protein using anti-SCAI antibody at 1/1,000 dilution.

Fig2: ICC staining SCAI in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: ICC staining SCAI in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Bon Opus Cat. #BA110795
Size
  • Host Species; Species Reactivity

    Mouse; Human
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, ICC, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Protein SCAI, Suppressor of cancer cell invasion protein
  • Background

    Protein SCAI, also known as Suppressor of cancer cell invasion protein, and encoded by the gene name SCAI, is a tumor suppressor that suppresses MKL1-induced SRF transcriptional activity. It is a regulator of cell migration and appears to be involved in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. SCAI localizes in the nucleus, where it binds and inhibits the myocardin-related transcription factor MAL by forming a ternary complex with serum response factor (SRF).(M1004-5)