RPS6KA2 Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis of RPS6KA2 on human RPS6KA2 recombinant protein using anti-RPS6KA2 antibody at 1/1,000 dilution.
Fig2: Western blot analysis of RPS6KA2 on HEK293 (1) and RPS6KA2-hIgGFc transfected HEK293 (2) cell lysate using anti-RPS6KA2 antibody at 1/1,000 dilution.
Fig3: Western blot analysis of RPS6KA2 on different cell lysate using anti-RPS6KA2 antibody at 1/1,000 dilution.
Positive control: Line1: Hela Line2: A431 Line3: HEK293 Line4: Jurkat Line5: HepG2 Line6: MCF-7 Line7: NIH/3T3
Host Species; Species ReactivityMouse; Human, Mouse
Application SummaryWB, ICC, IHC, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesHeat shock factor protein 1, Heat shock transcription factor 1
BackgroundThe family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development. The family of ribosomal S6 kinases includes p70 S6 kinase and p70 S6 kinase β, which are thought to have similar regulatory functions. MSK1 (also designated RLPK) is a novel Rsk-related protein, which, like the p90 Rsk family members, contains two non-identical complete kinase catalytic domains.(EM1706-43)