Reelin Recombinant Rabbit monoclonal Antibody IgG

Reelin Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112292-100µl
$279.00Price

Fig1: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Reelin antibody. Counter stained with hematoxylin.

Fig2: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-Reelin antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Reelin antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA112292
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Reelin
  • Background

    Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in "reeler" mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1 in a signaling pathway that controls cell positioning in the developing brain and is also thought to be a direct effector of the neurotrophin BDNF.(ET1704-98)

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