Recombinant Mouse Tacstd2/Trop2(C-6His)
Recombinant Mouse Tumor-associated calcium signal transducer 2 is produced by our Mammalian expression system and the target gene encoding Gln25-Gly270 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CB06
BackgroundTumor-associated calcium signal transducer 2(Tacstd2), also known as Cell surface glycoprotein Trop-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnamesTumor-associated calcium signal transducer 2;Tacstd2;Trop2;Cell surface glycoprotein Trop-2