Recombinant Mouse B-cell Maturation Protein/BCMA/TNFRSF17 (C-Fc)
Recombinant Mouse O88472 is produced by our expression system and the target gene encoding Met1-Thr49 is expressed Bon Opus Cat. #CS80
BackgroundB cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane domain, and a 113 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.
FormulationLyophilized from a 0.2 μm filtered solution of 20mMMES, 150mM NaCl, pH5.5.
ALTnamesTumor necrosis factor receptor superfamily member 17;TNFRSF17;B-cell maturation protein;CD269