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Recombinant Human Triosephosphate Isomerase/TIM (N-6His)

SKU: C260-10ug
$150.00Price
Recombinant Human Triosephosphate Isomerase is produced by our E.coli expression system and the target gene encoding Met1-Gln249 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #C260
Size
  • Accession Number

    P60174
  • Background

    Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. TPI has been found in nearly every organism searched for the enzyme, including animals such as mammals and insects as well as in fungi, plants, and bacteria. However, some bacteria that do not perform glycolysis, like ureaplasmas, lack TPI. TPI plays an important role in glycolysis and is essential for efficient energy production. TPI deficiency is an autosomal recessive disorder and the most severe clinical disorder of glycolysis. Triose phosphate isomerase deficiency is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection and characterized by chronic hemolytic anemia.
  • Expression

    E. coli
  • Packaging

    Dry ice/Polar packs
  • Formulation

    Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 1mM DTT, 10% Glycerol, pH 8.0.
  • ALTnames

    Triosephosphate Isomerase, TIM, Triose-Phosphate Isomerase, TPI1, TPI