Recombinant Human Phosphatidylinositol 4-Kinase β/PI4KB (C-6His)
Recombinant Human PI4KB is produced by our Mammalian expression system and the target gene encoding Met1-Met801 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C921
BackgroundPhosphatidylinositol 4-Kinase β (PI4KB) belongs to the PI3/PI4-kinase family and Type III PI4K subfamily. PI4KB contains one PI3K/PI4K domain and one PIK helical domain. It is highly expressed in heart, skeletal muscle, pancreas, testis and ovary,; it is lowly expressed in liver tissue. PI4KB kinase activity can be inhibited by wortmannin, and increased by interacting with NCS1/FREQ. PI4KB phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). In addition, PI4KB may regulate Golgi disintegration/reorganization during mitosis.
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of 25mM Tris.HCl,pH7.3,100mM glycine,10%glycerol.
ALTnamesPhosphatidylinositol 4-Kinase Beta, PI4K-Beta, PI4KBeta, PtdIns 4-Kinase Beta, NPIK, PI4K92, PI4KB, PIK4CB