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Recombinant Human Myelin Protein P0-like 1/MPZL1 (C-6His)

SKU: CI85-10ug
Recombinant Human Myelin Protein P0-like 1 is produced by our Mammalian expression system and the target gene encoding Ser36-Val162 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CI85
  • Accession Number

  • Background

    Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.
  • Expression

    Human Cells
  • Packaging

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
  • ALTnames

    Myelin protein zero-like 1, isoform CRA_b;cDNA FLJ78597, highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1), transcript variant 1, mRNA ;cDNA, FLJ96614, Homo sapiens myelin protein zero-like 1 (MPZL1), Mrna