top of page

Recombinant Human LIGHT/HVEM-L/TNFSF14/CD258 (N-6His)
Recombinant Human LIGHT is produced by our Mammalian expression system and the target gene encoding Leu83-Val240 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CM84

Recombinant Human LIGHT/HVEM-L/TNFSF14/CD258 (N-6His)

SKU: CM84-10ug
$110.00Price
Quantity
[{"key":"CM84-500ug","value":"Backorder"},{"key":"CM84-1mg","value":"Backorder"},{"key":"CM84-50ug","value":"Backorder"},{"key":"CM84-10ug","value":"Backorder"}]

Contact Us

Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

Distributors

Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

 

Additional $27 Ice Packs shipment fee is required for liquid proteins.

 

Please contact us to order for  international shipments.

Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
AAK26160.1
Species
Human
Expression System
Human Cells
Target Sequence
Leu83-Val240
Tag
N-His
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
Human TNFSF14 Protein, also known as LIGHT, belongs to a member of the tumor necrosis factor (TNF) ligand family. It can bind to NFRSF3/LTBR. It is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and it is also known as a herpesvirus entry mediator ligand (HVEML). TNFSF14 encodes a protein with a 37 aa cytoplasmic domain, 21aa transmembrane domain and 182 aa extracellular region. The gene is predominantly expressed in the spleen and also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines. TNFSF14 protein was found to probably function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. Studies have shown that this protein can prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Tumor necrosis factor ligand superfamily member 14; Herpes virus entry mediator ligand; TNFSF14; HVEM-L; LIGHT
Alternative Names
Be the first to submit a citation to get publication rewards
Citation
NA
Activity
bottom of page