Recombinant Human Inosine-5'-Monophosphate Dehydrogenase 2/IMPDH2 (N-6His)
Recombinant Human IMPDH2 is produced by our E.coli expression system and the target gene encoding Met1-Phe514 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CG79
BackgroundIMPDH2 is a cytosolic enzyme which belongs to the IMPDH/GMPR family. IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'- monophosphate. IMPDH2 is consequently involved in maintaining cellular guanine deoxy- and ribonucleotide pools required for DNA and RNA synthesis. In addition, IMPDH1 and IMPDH2 are targets for the important immunosuppressive drug, mycophenolic acid (MPA).
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of 20mM Tris 150mM NaCl pH 8.0 .
ALTnamesInosine-5'-monophosphate dehydrogenase 2, IMPDH2, IMP dehydrogenase 2, IMPD 2, IMPDH 2, IMPDH-II, IMPD2.