Recombinant Human Inosine-5'-Monophosphate Dehydrogenase 2/IMPDH2 (N-6His)

Recombinant Human Inosine-5'-Monophosphate Dehydrogenase 2/IMPDH2 (N-6His)

SKU: CG79-10ug
Recombinant Human IMPDH2 is produced by our E.coli expression system and the target gene encoding Met1-Phe514 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CG79
  • Accession Number

  • Background

    IMPDH2 is a cytosolic enzyme which belongs to the IMPDH/GMPR family. IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'- monophosphate. IMPDH2 is consequently involved in maintaining cellular guanine deoxy- and ribonucleotide pools required for DNA and RNA synthesis. In addition, IMPDH1 and IMPDH2 are targets for the important immunosuppressive drug, mycophenolic acid (MPA).
  • Expression

    E. coli
  • Packaging

    Dry ice/Polar packs
  • Formulation

    Supplied as a 0.2 μm filtered solution of 20mM Tris 150mM NaCl pH 8.0 .
  • ALTnames

    Inosine-5'-monophosphate dehydrogenase 2, IMPDH2, IMP dehydrogenase 2, IMPD 2, IMPDH 2, IMPDH-II, IMPD2.

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