Recombinant Human Fibronectin Fragment/RetroNectin/NovoNectin
Recombinant Human Fibronectin fragment is produced by our E.coli expression system and the target gene encoding Pro1270-Ser1546&Ala1721-Thr2016 is expressed. Bon Opus Cat. #CH38
BackgroundFibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containing a central cell-binding domain, a high affinity heparin-binding domain II,and CS1 site within the alternatively spliced III CS region of human fibronectin. Cells bind to a VLA-4 ligand, a CS-I site, and a VLA-5 ligand, a cell attachment domain, and virus vectors binds to a heparin binding domain II, which co-locates the cell and the virus vector on NovoNectin. This process enhances the density of both cells and vectors, and facilitates the gene transduction in the result.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ALTnamesNovoNectin,Fibronectin, FN, Cold-insoluble globulin, CIG, FN, Fibronectin 1