BackgroundDNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta/II small subunit family. POLD2 can form a heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. POLD2 possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. POLD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA).
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
ALTnamesDNA Polymerase Delta Subunit 2, DNA Polymerase Delta Subunit p50, POLD2