Recombinant Human Death Receptor 3/DR3/TNFRSF25 (C-Fc)

Recombinant Human Death Receptor 3/DR3/TNFRSF25 (C-Fc)

SKU: CJ74-10ug
Recombinant Human Death Receptor 3 is produced by our Mammalian expression system and the target gene encoding Gln25-Phe201 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CJ74
  • Accession Number

  • Background

    Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) contains 1 death domain and 4 TNFR-Cys repeats. TNFRSF25 is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation, activated by a monogamous ligand, known as TL1A (TNFSF15), which is rapidly upregulated in antigen presenting cells and some endothelial cells following Toll-Like Receptor or Fc receptor activation. This receptor has been shown to signal both through the TRADD adaptor molecule to stimulate NF-kappa B activity or through the FADD adaptor molecule to stimulate caspase activation and regulate cell apoptosis. It may play a role in regulating lymphocyte homeostasis.
  • Expression

    Human Cells
  • Packaging

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
  • ALTnames

    Tumor necrosis factor receptor superfamily member 25,APO3, DDR3, DR3, TNFRSF12, WSL, WSL1,TNFRSF25,Protein WSL-1,LARD,Protein WSL,Lymphocyte-associated receptor of death,Death receptor 3,Apoptosis-mediating receptor TRAMP,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apo-3
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