Recombinant Human Apolipoprotein C-II/APOC2 (C-6His)
Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Met1-Glu82 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CB66
BackgroundAPOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of 20mMPB,150mM NaCL,30%glycerol,pH7.2.
ALTnamesApolipoprotein C-II, Apolipoprotein C2, APC2 and APOC2