BackgroundAlpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of 50mM Tris, 150mM NaCl, 40% Glycerol, pH 7.4.
ALTnamesAlpha-Parvin, Actopaxin, CH-ILKBP, Calponin-Like Integrin-Linked Kinase-Binding Protein, Matrix-Remodeling-Associated Protein 2, PARVA, MXRA2