Recombinant Cynomolgus Tumor Necrosis Factor Ligand 2B/OX40L(N-8His)
Recombinant Cynomolgus monkey OX40 Ligand is produced by our Mammalian expression system and the target gene encoding Gln51-Leu183 is expressed with a 8His tag at the N-terminus. Bon Opus Cat. #CP72
BackgroundTumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ALTnamesTumor necrosis factor ligand 2B; TNFSF4; OX-40L