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Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

SKU: C960-10ug
$105.00Price
Recombinant Cynomolgus CD27 molecule is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C960
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  • Accession Number

    F7BYS2

  • Background

    CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7，belongs to the TNF-receptor superfamily. CD27 is a single-pass type I membrane protein and exists as a homodimer form, containing three TNFR-Cys repeats. CD27 transduces signals that lead to the activation of NF-KappaB and MAPK8/JNK. CD27 is involved in regulating B-cell activation and immunoglobulin synthesis, binding to the ligand CD70. TRAF2 and TRAF5 have been shown to mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to CD27 and is thought to play a key role in the apoptosis. CD27 is required for generation and long-term maintenance of T cell immunity.

  • Expression

    Human Cells

  • Packaging

    Ambient

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 20mMTris,150mM NaCl,pH8.5.

  • ALTnames

    CD27 Antigen; CD27L Receptor; T-Cell Activation Antigen CD27; T14; Tumor Necrosis Factor Receptor Superfamily Member 7; CD27; CD27; TNFRSF7