PP2A (alpha+beta) Rabbit polyclonal Antibody IgG

SKU: BA110561-100µl
$279.00Price

Fig1: Western blot analysis on different cell lysates using anti-PP2A(alpha+beta) rabbit polyclonal antibody. Positive control: 

Lane 1: A431      

Lane 2: HepG2 

Lane 3: F9        

Lane 4: PC-12

Fig2:  Immunocytochemical staining of Hela cells using anti-PP2A(alpha+beta) rabbit polyclonal antibody.

 

Bon Opus Cat. #BA110561
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Peptide
  • Application Summary

    WB, ICC, IHC, FC
  • Purification; Formulation

    Peptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform,Replication protein C
  • Background

    In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2Aβ and PP2A∫. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-α and -A-β, PP2A-B-α and -B-β, PP2A-C-α and -C-β, PP2A-B56-α and -B56-β.(R1510-31)

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