PKC mu Recombinant Rabbit monoclonal Antibody IgG

SKU: BA113149-100µl

Fig1:  Western blot analysis of PKC mu on different cell lysate using anti-PKC mu antibody at 1/1,000 dilution.

Positive control:  

Lane 1: Hela             

Lane 2: Mouse kidney    

Lane 3: PC12



Bon Opus Cat. #BA113149
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Background

    Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.(ET1705-4)

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