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PDX1 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112380-100µl

Fig1: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody. Counter stained with hematoxylin.

Fig2: IF analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody (green). The nuclear counter stain is DAPI (blue).


Bon Opus Cat. #BA112380
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

    Recombinant protein
  • Application Summary

  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Pancreas/duodenum homeobox protein 1, Glucose-sensitive factor, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, Somatostatin-transactivating factor 1
  • Background

    Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.(ET1705-99)