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©2020 by Bon Opus Biosciences, LLC.

PDI Rabbit polyclonal Antibody IgG

SKU: BA110542-100µl
$279.00Price

Fig1: Western blot analysis of PDI on different cell lysates using anti- PDI antibody at 1/1000 dilution.

Positive control:   

Lane 1: Hela            

Lane 2: MCF-7 

Lane 3: PANC            

Lane 4: HepG2 

Lane 5: HUVEC           

Lane 6: NIH/3T3 

Lane 7: L929            

Lane 8: F9 

Lane 9: Jurkat          

Lane 10: A431 

Lane 11: A549           

Lane 12: Mouse liver 

Lane 13: Mouse kidney   

Lane 14: Mouse brain 

Lane 15: Human kidney   

Lane 16: Human brain 

Lane 17: Human liver

Fig2: ICC staining PDI in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: ICC staining PDI in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Bon Opus Cat. #BA110542
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Peptide
  • Application Summary

    WB, ICC, IHC
  • Purification; Formulation

    Peptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Protein disulfide-isomerase A2,Pancreas-specific protein disulfide isomerase
  • Background

    Protein disulfide isomerase or PDI is an enzyme in the endoplasmic reticulum in eukaryotes that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. Another major function of PDI relates to its activity as a chaperone; i.e., it aids wrongly folded proteins to reach a correctly folded state without the aid of enzymatic disulfide shuffling. PDI has been found to be involved in the breaking of bonds on the HIV gp120 protein during HIV infection of CD4 positive cells, and is required for HIV infection of lymphocytes and monocytes.(ER40404)