PCNA Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on Raji (1) and F9 (2) cell lysates using anti-PCNA rabbit polyclonal antibodies.
Fig2: Immunofluorescent staining of Hela cells using anti- PCNA rabbit polyclonal antibody.
Fig3: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-PCNA rabbit polyclonal antibody.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, ICC, IHC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesProlifeRating cell nuclear antigen,Cyclin
BackgroundProliferating cell nuclear antigen (PCNA) is a member of the DNA sliding clamp family of proteins that assist in DNA replication. Crystal structure data suggests that a PCNA homotrimer ring can encircle and slide along the DNA double helix. Multiple proteins involved in DNA replication, DNA repair, and cell cycle control bind to PCNA rather than directly associating with DNA, thus facilitating fast processing of DNA. PCNA protein expression is a well-accepted marker of proliferation.(R1306-5)