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PAX9 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA111860-100µl
$279.00Price

Fig1: Western blot analysis of PAX9 on different lysates using anti-PAX9 antibody at 1/1,000 dilution.

Positive control:   

Lane 1: HepG2             

Lane 2: Hela

 

 

Bon Opus Cat. #BA111860
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Paired box protein Pax-9
  • Background

    Pax genes contain paired domains with strong homology to genes in Droso-phila which are involved in programming early development. Pax-9, a member of the paired box-containing gene family, is closely related in its paired do-main to Pax-1. The Pax-9 gene encodes the highly conserved paired domain and the gene is a member of the same subgroup as Pax-1/undulated. Pax-9 is essential for the development of a variety of organs and skeletal elements. Mutations in either the Pax-1 or the Pax-9 genes may produce an inherited skeletal disorder such as the Jarcho-Levin syndrome or other forms of spondylocostal dysplasia, conditions resembling “undulated” in the mouse. A frameshift mutation within the paired domain of Pax-9 was identified in a family segregating autosomal dominant oligodontia whose members had normal primary dentition but lacked most permanent molars. In addition to lack of permanent molars, some individuals also lacked maxillary and/or mandibular second premolars, as well as mandibular central incisors. The gene which encodes Pax-9 maps to human chromosome 14q12-q13.(ET1612-59)