Pan-Cadherin Recombinant Rabbit monoclonal Antibody IgG

SKU: BA111596-100µl

Fig1: Western blot analysis of Pan-Cadherin on different lysates using anti-Pan-Cadherin antibody at 1/1,000 dilution.

Positive control:   

Lane 1: Human heart      

Lane 2: Mouse heart 

Lane 3: Rat heart

Fig2: ICC staining Pan-Cadherin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Pan-Cadherin antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA111596
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Cadherin-1, CAM 120/80, Epithelial cadherin, Uvomorulin, CD_antigen: CD324, Cadherin-2, CDw325, Neural cadherin, CD_antigen: CD325, Cadherin-3, Placental cadherin, 7B4 antigen, Vascular endothelial cadherin, CD_antigen: CD144, Cadherin-4, Retinal cadherin
  • Background

    Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as -catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin, R-cadherin, B-cadherin, E/P cadherin and cadherin-5.(ET1609-70)

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