p53 Mouse monoclonal Antibody IgG2b

SKU: BA110528-100µl

Fig1: Western blot analysis of p53 on different cell lysates using anti-p53 antibody at 1/1000 dilution.

Positive control:   

Lane 1: 293T              

Lane 2: A431

Fig2: ICC staining p53 in A431 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: Immunohistochemical analysis of paraffin-embedded human colonic carcinoma tissue using anti-p53 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA110528
  • Host Species; Species Reactivity

    Mouse; Human
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, ICC, IHC, FC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Cellular tumor antigen p53,Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53
  • Background

    p53 (also known as protein 53 or tumor protein 53), is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer. As such, p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation.(EM20603)

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