OCT-4 Mouse monoclonal Antibody IgG1

SKU: BA110519-100µl
Bon Opus Cat. #BA110519
  • Host Species; Species Reactivity

    Mouse; Human, Mouse
  • Immunogen

  • Application Summary

    WB, ICC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    POU domain, class 5, transcription factor 1,Octamer-binding protein 3,Octamer-binding protein 4,Octamer-binding transcription factor 3
  • Background

    Oct-4 (POU5F1) is transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). It forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Oct-4 is critical for early embryogenesis and for embryonic stem cell pluripotency. It is expressed in developing brain and highest levels also found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.(EM100306)

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